Tegonat 20 (Tegafur/Gimeracil/Oteracil)

Tegonat 20: Comprehensive Guide

Tegonat 20 is an anticancer drug used in the treatment of advanced cancers of the stomach and metastatic cancer of the rectum and large intestines. This combination chemotherapy medication contains three active constituents namely Tegafur, Gimeracil, and Oteracil.

Gimeracil potentiates the cytotoxic effect of 5-FU by preventing its lysis, while uracil protects normal gastrointestinal mucosa from the adverse effects of 5-FU like severe diarrhea and mucositis. This drug is administered orally and in cycles as per the oncologist's recommendation. It should be avoided during pregnancy because it can cause fetal harm.

What Is Tegonat 20?

Tegliptin 20 Capsule is an anti-diabetic and is prescribed to patients who suffer from type 2 diabetes, in whom their blood sugar cannot be regulated through diet and exercise alone. The Teneligliptin used is classified as a DPP-4 inhibitor and it is primarily a prescription medicine that helps inhibit the action of a certain hormone in the body that leads to the degradation of the effects of insulin while it enhances your liver to increase more insulin release in your body.

This medicine relaxes your blood vessels and improves the flow of blood in your body. It also relieves edema, which is a buildup of fluid in the body, by increasing urine output. It is a prescription medication and should be taken as directed by your doctor.

It is also important to have a healthy lifestyle while on this medication, which includes losing weight if overweight, eating less food, and getting more exercise. You should also avoid drinking alcohol while on this medicine.

How Does Tegonat 20 Work?

Tegonat 20 Capsule is used for hypertension, heart failure, and edema. It helps remove the excess fluid from the body which reduces the load on the heart and renders it more effective. It further reduces ededema theewelling of hands, feet, arms, ankles, and legs, caused by the accumulation of fluid in the body.

It is a combination chemotherapy drug that contains the active ingredients Tegafur, Gimeracil, and Oteracil. It is also used in combination with other anticancer medications to treat head and neck cancer, colorectal cancer, non-small cell lung cancer, breast cancer, and pancreatic cancer.

How Should Tegonat 20 Be Used?

Tegonat-20 Capsule is used in the treatment of high blood pressure, heart failure, and edema (fluid build-up). This leads to a decrease in the amount of fluid and salt held by the kidneys, thus lowering your blood pressure and reducing the strain on your heart. Tegonat-20 Capsule should be taken exactly as instructed by a doctor. Do not stop taking this medicine without consulting your doctor even though you may feel better. This will give you an increased chance of getting side effects.

You should not take Tegonat-20 Capsules if you are allergic to it or any of its ingredients. This medicine may cause dizziness, drowsiness, or light-headedness in some people. Tegonat-20 Capsule is not recommended for adolescents and children under 18.

The Benefits of Taking Tegonat 20

This drug is for treating certain kinds of cancer (tumors). It helps slow or stop the growth of tumor cells. Side effects are possible with this medicine. Be sure to report the following to your doctor if you experience any of them: drooling, loss of balance control, muscle trembling or stiffness, shuffling walk, trouble thinking clearly, or uncontrolled movements of your arms or legs (extrapyramidal symptoms). Your doctor will adjust your dose or dosing schedule as necessary.

Take Indian Tegafur/Gimeracil/Oteracil Capsule exactly as directed by your physician. Do not increase the dose or duration of the treatment and take it for an extended period unless it is prescribed by your doctor. This drug will decrease the number of blood cells in your body. This might make you vulnerable to infections. Monitor your blood cell count periodically while on this medication. This drug is not approved for use in adolescents and children less than 18 years of age.

Tegonat 20 side effects

Tegonat 20 can cause feelings of tingling, burning, pain, or numbness in the arms and legs. You could find that your ability to walk or get around is a bit impaired by such sensations. Share these side effects with your physician. Dosing or application might have to be changed. Use caution if you become pregnant while on this drug. It comes out in the milk and may endanger an infant. Inform your physician before nursing an infant. This medication is not indicated for use in adolescents below the age of 18 years.

Tegonat 20 is the brand name of a combination chemotherapy used for advanced stomach cancer, head and neck, and metastatic cancers in other body parts. This is a preparation of tegafur that inhibits DNA and RNA synthesis and functioning within the cells. It will halt the formation of cancerous cells. Gimeracil prevents the lysis of tegafur by normal gastrointestinal mucosa, thus maintaining high concentrations of tegafur and reducing gastrointestinal toxicity.

Dosage

Tegonat is a combination chemotherapy drug that contains the active ingredients tegafur, gimeracil, and uracil. It is used in the treatment of advanced Stomach Cancers and metastatic cancer of the large intestine and rectum. It is not approved for use in adolescents and children less than 18 years of age and may be administered alone or in combination with other anticancer drugs.

It should be known that if you have a critical blood disorder, kidney disorder, viral infections, or know that you are suffering from DPD (enzyme dihydropyrimidine dehydrogenase) deficiency, report this to your healthcare provider. Your physician should also be informed if you are breastfeeding. It has lactose and has to be used carefully if you have an intolerance to sugars.

All analytical grade reagents such as hydrochloric acid, trifluoroacetic acid, sodium hydroxide, and methanol were bought from Merck. Throughout the analysis, Milli-Q water was used. Shree Icon Labs provided Tegafur, gimeracil, oteracil potassium, and working standards of TFGR, GMRL, and ORCL.

Warning & Precautions

This medication contains several ingredients that may cause serious allergic reactions. Get Seek emergency medical care if you have symptoms such as a rash, itching, trouble breathing or swallowing, swelling of the hands, face or lips, hives, fever, chills, sore throat, cough or hoarseness, painful or difficult urination, darkened stools or blood in urine or stool.

Some people taking this drug have become unable to have children. Talk to your doctor about whether you should take fertility drugs to increase your chances of having children while you're on this medication. This medication can increase your chances of developing seizures. If you have had seizures, your doctor will keep a close watch over you while you're on this medication. This drug may also increase eye pressure and cause glaucoma, so inform your doctor if you have a history of glaucoma or increased eye pressure.

Other side effects can be nausea, vomiting, diarrhea, and constipation. This medicine may also drowsiness and headaches. Avoid driving or engaging in any work that requires full alertness till you know how you react to this medicine. Tegonat 20 Capsule is best taken 1 hour before or after a meal.

Frequently Asked Questions (FAQs)

1 Is Tegonat 20 mg a steroid?

No, it is not a steroid. It is an immunomodulatory agent.

2 How long does it take for Tegonat 20 to work?

Some people notice improvements within a few months, but it takes longer for the full benefits to be realized.

3 What are the common side effects of Tegonat?

Headache, fatigue, joint pain, and flu-like symptoms.

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