Niclosig 500 Mg (Niclosamide)
| Active Ingredient: | Niclosamide |
|---|---|
| Indication: | Worm infections |
| Manufacturer: | HAB Pharmaceuticals & Research Ltd |
| Packaging: | 10 tablets in 1 strip |
| Strength: | 500mg |
| Delivery Time: | 6 To 15 days |
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Description
What is Niclosig 500 Mg?
Niclosig 500 Mg is an anthelmintic medication. It works by killing tapeworms that cause Worm infection. These dead worms are then passed out in the stool. This medicine is used to treat a variety of parasitic worm infections.
Your doctor will check your blood counts and liver function before giving you this drug and regularly during your treatment. If you get side effects, please inform your doctor as soon as possible, particularly regurgitation, vomiting, or stomach upset.
Niclosig 500 Mg Uses
Niclosig 500 mg contains Niclosamide, an anthelmintic (anti-worm) medication primarily used to treat tapeworm infections in the intestines. It works by inhibiting the parasite’s ability to absorb glucose, leading to its death and eventual elimination from the body through stool.
1 Treatment of Tapeworm Infections – It is effective against various tapeworm species, including Taenia saginata (beef tapeworm), Taenia solium (pork tapeworm), and Diphyllobothrium latum (fish tapeworm).
2 Hymenolepiasis (Dwarf Tapeworm Infection) – Used to treat infections caused by Hymenolepis nana, commonly affecting children.
3 Off-label Use for Other Parasitic Infections – Some research suggests its potential use against other intestinal parasites.
4 Possibly antiviral and anticancer actions – Research continues using it against viral infections and specific cancers, but much more research is needed.
How to Take Niclosamide?
The repurposing of existing drugs is an increasingly important aspect of drug discovery as it provides a quicker, cheaper, and more effective route to the development of new medications. Drugs that have been repurposed often show activity against diseases for which few other drugs are available. A prime example of such a drug is niclosamide, which was originally developed by Bayer in the 1950s as a molluscicide to kill snails that are intermediate hosts of the parasitic disease schistosomiasis.
It is a highly potent inhibitor of endothelia, a natural substance that causes blood vessels to narrow. Niclosamide blocks this action, allowing blood vessels to relax and reducing strain on the heart and lungs. It is used for the treatment of pulmonary arterial hypertension (PAH).
How Does Niclosig 500 mg Work?
To see if any conversion into its monohydrate occurs from anhydrous niclosamide, dissolution-stirring experiments were undertaken using whole tablets of widely commercially available niclosamide Yomesan (Bayer, Germany). Since their excipient compositions were similar to those of Yomesan, their dissolution data gave very similar results. This result implies that compounding pharmacies could easily prepare solutions using these recipes, thus potentially increasing niclosamide availability and distribution.
Dosage of Niclosig 500 Mg
The anthelmintic medication, in the form of the tablet Niclosig 500 mg, functions by killing the tapeworms that may be causing an infection; these dead worms are subsequently excreted in the stool. A patient taking this medicine should strictly follow their doctor’s prescription instructions and not skip doses or discontinue use upon improvement. The doctor will require checking the blood count and liver function before the initiation of this drug and its use. This medicine is known to have harmful effects on unborn babies. Use birth control measures while taking this drug to prevent pregnancy. Avoid alcohol consumption and other medications while taking this drug.
The Niclosig 500 Mg Tablet powder was weighed to obtain the total Yomesan material and then converted to niclosamide equivalents based on typical talc and corn starch contents of the tablet as binders and disintegrates, respectively. These tablet materials were dissolved in either pH 7.2 or pH 9.36 Tris buffers at room temperature. The buffers were stirred at 500 rpm with a magnetic stir bar until a maximum of 240 min (4 h) had passed. A yellow coloration of the supernatant indicating that niclosamide had dissolved was observed by this time.
Side effects of Niclosig 500 Mg
This medicine helps cure parasitic worm infections by killing the worms and stopping further development. The killed worms are then excreted with the stool. This medicine will generally cause you to become more comfortable soon after starting on it. Yet, you need to keep taking this medicine as long as the doctor has directed you to continue it, even if you do feel better. That way you will ensure all the worms have been killed and prevent them from becoming resistant to this medicine.
This medication can increase your risk for a severe condition called Fournier’s gangrene, which damages tissue in the perineum- the area of space located between and around the anus and genitals.
Warnings & Precautions
Niclosig 500 mg (Niclosamide) is an anthelmintic medication used to treat Worm infections. Before using this medication, consult a doctor to ensure it is appropriate for your condition.
Warnings:
- Avoid use if allergic to Niclosamide or similar drugs.
- Not recommended for children under 2 years without medical supervision.
- May cause gastrointestinal issues such as nausea, vomiting, or diarrhea.
- Not suitable for systemic infections, as it only acts within the intestine.
Precautions:
- Take the full course as prescribed to prevent resistance.
- Pregnant and breastfeeding women should consult a doctor before use.
- Can interact with alcohol and other medications—inform your healthcare provider about any ongoing treatments.
- Maintain proper hygiene to prevent reinfection.
Frequently Asked Questions
1 How does Niclosig 500 mg work?
It kills worms responsible for infection. The killed worms are then passed in the stool.
2 What infections does Niclosig 500 mg treat?
It is mainly used in the treatment of Worm infections.
3 Is Niclosig 500 mg effective?
Use the dose and duration advised by your doctor for effective Niclosig 500 mg Tablet. Never stop using the drug even when you notice improvements in your condition. The symptoms may come back or worsen if you discontinue the medication too early.
4 Can I consume alcohol while taking Niclosig 500 mg?
It is unsafe to consume alcohol while taking Niclosig 500 mg Tablet.
1 review for Niclosig 500 Mg (Niclosamide)
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Patrick Carpenter –
Niclosig 500 mg is an excellent medicine. Worked like a charm!